Urine Test for Diastase.
Urine test for diastase (amylase) is a biochemical analysis aimed at determining the level of the enzyme diastase (alpha-amylase) in urine. Diastase is an enzyme involved in carbohydrate breakdown, predominantly produced by the pancreas. This test helps diagnose pancreatic diseases, assess treatment effectiveness, and detect other pathologies.
Indications for the test:
- Suspected acute or chronic pancreatitis.
- Cysts and tumors of the pancreas.
- Monitoring treatment of pancreatic diseases.
- Inflammatory processes in the gastrointestinal tract, liver, kidneys.
- Symptoms such as band-like abdominal pain, nausea, vomiting, loss of appetite, and fever.
Collection and testing methodology:
- The test uses a midstream portion of morning urine after hygiene procedures.
- In some cases, urine collection for 2 hours or 24 hours is prescribed for improved accuracy.
- Samples should be delivered to the laboratory as quickly as possible, preferably within 10 minutes of collection.
- The analysis is performed by a kinetic method.
Normal values:
- Urine diastase level in adults usually ranges from 16 to 64 U/L, in children from 10 to 64 U/L.
- Levels may be lower in women and may vary during pregnancy and certain conditions.
Interpretation of results:
- Elevated diastase may indicate acute pancreatitis, inflammatory diseases of the liver and bile ducts, tumors, pancreatic injury, and other inflammatory processes.
- Decreased diastase levels occur in chronic pancreatitis, severe hepatitis, renal failure, cystic fibrosis, and after pancreas removal.
- For accurate diagnosis, the urine diastase test is usually complemented with other studies and clinical evaluation.
Preparation for the test:
- For 24 hours before the test, it is recommended to avoid alcohol, fatty and spicy foods.
- Avoid physical exertion and taking medications without consulting a doctor.
- Observe genital hygiene before urine collection.
The urine test for diastase is an important diagnostic tool for assessing pancreatic condition and detecting digestive system pathologies.