PCT Plateletcrit
PCT (Plateletcrit) is a parameter reflecting the volumetric proportion of platelets in the total blood volume, analogous to hematocrit (HCT) for red blood cells. It is calculated as the product of platelet count (PLT) and their mean volume (MPV), expressed as a percentage.
Normal PCT values:
- 0.12 – 0.36 %
- May vary depending on sex, age, and laboratory methods
Physiological significance:
- Assesses the overall contribution of platelets to blood volume
- Serves as a marker for thrombotic or hemorrhagic risk
- Helps in comprehensive evaluation of blood coagulation
PCT is elevated in:
- Myeloproliferative disorders (e.g., essential thrombocythemia)
- Atherosclerosis and other vascular diseases
- Inflammations and infections
- Iron deficiency anemia
- Post-surgery, trauma, or massive bleeding
PCT is decreased in:
- Thrombocytopenia (low platelet count)
- Bone marrow hematopoiesis disorders
- Oncohematological diseases (leukemia, myelodysplasia)
- Chemotherapy or radiotherapy
- Vitamin B12 and folate deficiency
Why PCT is measured:
- For early detection of thrombotic or bleeding tendencies
- To monitor blood and coagulation system diseases
- During oncological, hematological, and inflammatory processes
How the test is performed:
- The parameter is calculated automatically during a complete blood count
- Blood is drawn fasting, preferably in the morning
Important:
- PCT is used diagnostically only in combination with other platelet indices: PLT, MPV, PDW
- Accurate result interpretation requires consultation with a physician