Urine Test for Diastase

Urine test for diastase (amylase) is a biochemical analysis aimed at determining the level of the enzyme diastase (alpha-amylase) in urine. Diastase is an enzyme involved in carbohydrate breakdown, primarily produced by the pancreas. The test helps diagnose pancreatic diseases, evaluate treatment effectiveness, and detect other pathologies.
Indications for the test:

Suspected acute or chronic pancreatitis.
Cysts and tumors of the pancreas.
Treatment monitoring of pancreatic diseases.
Inflammatory processes in the gastrointestinal tract, liver, kidneys.
Symptoms: band-like abdominal pain, nausea, vomiting, loss of appetite, fever.

Collection and testing methodology:

Midstream morning urine after hygiene procedures is used for analysis.
In some cases, 2-hour or 24-hour urine collection is prescribed for higher accuracy.
Samples should be delivered to the laboratory as soon as possible, preferably within 10 minutes after collection.
The test is performed using a kinetic method.

Normal values:

Urinary diastase level in adults usually ranges from 16 to 64 U/L, in children from 10 to 64 U/L.
Women may have lower levels, which can vary during pregnancy and certain conditions.

Result interpretation:

Elevated diastase levels may indicate acute pancreatitis, inflammatory diseases of the liver and bile ducts, tumors, pancreatic injury, and other inflammatory processes.
Reduced diastase levels are seen in chronic pancreatitis, severe hepatitis, kidney failure, cystic fibrosis, and after pancreas removal.
For accurate diagnosis, the urine diastase test is usually complemented by other tests and clinical evaluation.

Preparation:

Avoid alcohol, fatty and spicy foods 24 hours before the test.
Avoid physical exertion and medications without doctor’s approval.
Maintain genital hygiene before urine collection.

Urine test for diastase is an important diagnostic tool to assess pancreatic health and detect digestive system pathologies.