Cholesterol and Lipids

Cholesterol is a fat-like substance essential for building cell membranes, hormone synthesis, and bile acid production. Cholesterol is transported in blood as part of lipoproteins of different densities — LDL (low-density lipoproteins) and HDL (high-density lipoproteins). Blood lipids include cholesterol, triglycerides, and phospholipids — key components of fat metabolism. Lipid metabolism disorders can lead to atherosclerosis — buildup of fatty plaques in blood vessel walls, increasing the risk of cardiovascular diseases, heart attacks, and strokes. What is assessed in the lipid profile:
  • Total cholesterol — the overall level of all cholesterol types in blood.
  • LDL (“bad” cholesterol) — promotes fat deposits in vessel walls.
  • HDL (“good” cholesterol) — helps remove excess cholesterol from vessels and protects against atherosclerosis.
  • Triglycerides — the main form of fat in the body; elevated levels also increase cardiovascular risk.
Why cholesterol and lipid tests are done:
  • To assess risk of atherosclerosis and ischemic heart disease.
  • Diagnosis and monitoring of dyslipidemia treatment.
  • Monitoring patients with diabetes and obesity.
How the test is done:
  • Blood is drawn from a vein fasting (at least 8 hours without food).
  • Avoid heavy food and alcohol for at least a day before the test.
  • Refrain from intense physical activity the day before the test.
Important to know:
  • Lipid levels are closely related to lifestyle, diet, and genetics.
  • Changes in lipid levels often do not show symptoms; regular monitoring is important for preventing complications.
  • Additional research methods and doctor consultation may be needed for accurate risk assessment.